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Distribution and Expression of Visfatin-Positive Cells in the Spleen of Lipopolysaccharide-Stimulated Piglets International Journal of Morphology
Xiao,Ke; Qiu,Chang-Wei; Chen,Min; Yang,Zhi; Wang,Jing; Peng,Ke-Mei; Song,Hui.
The histological changes in the spleen and the immunohistochemical expression of visfatin in lipopolysaccharide-stimulated piglets are reported to examine the relation between visfatin and inflammation. The results are as follows: (1) After LPS treated, the spleen displayed thicker capsules and trabecula, the thinner periarterial lymphatic sheath, and the more expandable splenic sinusoid, with an increase in the number of splenic nodules, lymphocytes, ellipsoids of the marginal zone, red blood cells and macrophagocytes. (2) Visfatin-positive cells were mainly distributed in the red pulp of the spleen, with less in splenic nodules and periarterial lymphatic sheath. In the LPS-treated group, the signal intensity and quantity of the visfatin-positive cells...
Tipo: Journal article Palavras-chave: Visfatin; Spleen; Lipopolysaccharide; Piglets.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400052
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